Translocation t(8;22) and monosomy 7 in a case of acute lymphoblastic leukemia expressing myeloid markers.
نویسندگان
چکیده
The simultaneous coexpression of lymphoid and myeloid markers has been observed in some cases of childhood acute lymphoblastic leukemias (ALL). In this paper, we describe a 6-year-old male patient with an ALL expressing myeloid antigens in whom a novel karyotypic association, t(8;22) and monosomy 7, and high Ag-NOR activity were found concomitantly with a very short survival.
منابع مشابه
B cell acute lymphoblastic leukemia associated with t(8;22)(p11.2q11.2): Role of additional cytogenic anomalies
B lymphoblastic leukemia (B-ALL) may be associated with recurrent cytogenetic and molecular abnormalities. We describe the fourth-known case of B-ALL associated with the t(8;22)(p11.2q11.2) – a translocation seen more frequently in T lymphoblastic leukemia and acute myelogenous leukemia. This patient’s leukemia involves a combination of additional cytogenetic anomalies not yet described in the ...
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عنوان ژورنال:
- Haematologica
دوره 80 6 شماره
صفحات -
تاریخ انتشار 1995